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睾丸胚細胞性腫瘍 Testicular germ cell tumors

testicular-GCT-IHC.jpg

免疫染色による睾丸胚細胞性腫瘍の鑑別診断(右図)

WHO (2016) classification

Germ cell tumors derived from germ cell neoplasia in situ

Noninvasive germ cell neoplasia

  • Germ cell neoplasia in situ
  • Specific forms of intratubular germ cell neoplasia

Tumors of a single histological type (pure forms)

  • Seminoma
  • Seminoma with syncytiotrophoblast cells

Nonseminomatous germ cell tumors

  • Embryonal carcinoma
  • Yolk sac tumor, postpubertal type
  • Trophoblastic tumors
    • Choriocarcinoma
    • Nonchoriocarcinomatous trophoblastic tumors
    • Placental site trophoblastic tumor
    • Epithelioid trophoblastic tumor
    • Cystic trophoblastic tumor
  • Teratoma, postpubertal type
  • Teratoma with somatic type malignancy

Nonseminomatous germ cell tumors of more than one histological type

  • Mixed germ cell tumors Germ cell tumors of unknown type
  • Regressed germ cell tumors

Germ cell tumors unrelated to germ cell neoplasia in situ

Spermatocytic tumor

Teratoma, prepubertal type

  • Dermoid cyst
  • Epidermoid cyst
  • Well differentiated neuroendocrine tumor (monodermal teratoma)

Mixed teratoma and yolk sac tumor, prepubertal type

Yolk sac tumor, prepubertal type


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Last-modified: 2020-06-18 (木) 19:59:16 (51d)